DEVELOPMENT OF ADDITIVE BIOPOLYMER HEALING COVERAGE WITH ALOE VERA

Authors

DOI:

https://doi.org/10.26853/Refas_ISSN-2359-182X_v10n03_06

Keywords:

Biopolymers, Aloe vera, Curative coverage, Product development, PERMATUS

Abstract

With technological advancement, there is a need to develop alternative products that are more accessible to people, using production processes that respect the environment, while establishing innovative and more economical techniques, making production methods cheaper. Selection of renewable biopolymeric materials, such as: carbohydrates, lipids and proteins for manufacture of pharmaceutical raw materials for use in curative treatments is very promising, since it allows the increase of bioactive dressings. Treatment of chronic wounds demands a lot of time and resources, moreover, it exposes the patient to high risks of complications, such as lower limb amputations in diabetic patients, which can lead to serious secondary infections due to antibiotic resistance and even death. The dressing, to be considered biocompatible, must have certain essential characteristics, such as keeping the wound bed moist, removing exudate, protecting the wound from the action of pathogenic microorganisms and not causing allergic reactions to the patient. There are records from prehistory of the use of medicinal plants in the treatment of diseases by means of potions containing plant extracts for therapeutic purposes. The use of Aloe vera extract, in treatment of wounds, allows for more oxygenation of the lesion, increases vascularization and the amount of collagen, which is an essential protein for tissue regeneration, so that healing occurs, in which the tissue is deflated and remodeled, promoting greater multiplication of skin cells. This study aims to use the design, according to Baxter, in the product development processes, to elaborate biopolymeric material, added with glycolic extract of Aloe vera and will be applied in the development of a bioactive dressing for treatment of chronic wounds and to carry out an experimental study by PERMATUS model of developed product of the curative coverage.  

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Author Biographies

Neir Ligabo Jr., Centro Universitário Teresa D'Ávila - UNIFATEA

He holds a Bachelor's degree in Pharmacy from Faculdade de Pindamonhangaba (2009), a Degree in Chemistry from Cruzeiro do Sul University, a Postgraduate degree in Pharmacology and Drug Interactions from Uninter (2015), a Professional Master's Degree in Design, Technology and Innovation from UNIFATEA? CENTRO UNIVERSITÁRIO TERESA D?ÁVILA (scholarship holder - 2020), and specialist in Homeopathic Pharmacy by UNYLEYA (2021). Currently studying Pedagogy at UNIFATEA (scholarship). Pharmacist - gazetted at the Municipality of Lorena, assuming since 2022 the position of Coordinator of Pharmaceutical Assistance in the municipality of Lorena/SP, professor at the faculty of pharmacy at the Teresa D`Ávila University Center and was a professor at the Patrocínio de São José and Delta technical schools in various technical courses.

José Wilson de Jesus Silva, UNIFATEA

Do you have a Post-Doctorate in Materials Engineering from UNESP? Guaratinguetá Campus (2015), PhD in Mechanical Engineering from UNESP? Guaratinguetá Campus (2011), Masters in Mechanical Engineering from UNESP? Guaratinguetá Campus (2003) and Degree in Civil Engineering from UNESP? Guaratinguetá Campus (2000). He was Full Professor I and Coordinator of the Jewelry Design Laboratory at Centro Universitário Teresa D?Ávila - UNIFATEA, Professor of the Stricto Sensu Postgraduate Program, UNIFATEA - Professional Master's Degree in Design, Technology and Innovation, Professor of the Architecture and Urban Planning course - UNIFATEA from 2011 to 2022 and also a collaborating professor in the chemistry department at UNESP, Guaratinguetá Campus. He has experience in teaching, research and extension in the areas of Industrial Design, Niobium Jewelry Design, Foreign Languages, Civil Engineering, Mechanics and Production, with an emphasis on New Materials, Experiment Planning, Corrosion, Microstructural Characterization and Supply Chain Management .

Rosinei Batista Ribeiro, CEETEPS - Undiade de Pós-Graduação, Extensão e Pesquisa

Post-Doctorate at the Technological Institute of Aeronautics (ITA) at the Institute of Advanced Studies - IEAv, Department of Aerospace Science and Technology - DCTA - 2020. Doctorate and Masters in Mechanical Engineering from UNESP- FEG. Permanent Professor in the Professional Master's Program in Management and Technology in Production Systems, leader of the Research Group "Management of Technological Innovation and Sustainability - DGP/CNPq" at the Paula Souza State Center for Technological Education - CEETEPS - Postgraduate Unit, Extension and Research - UPEP and Professor III - G at the Faculties of Technology of the State of São Paulo, Units of Guaratinguetá and Cruzeiro, SP. Consultant - CAPES and participation in the Forum of coordinators of PPGs and the Working Group (GT) of the Architecture and Urbanism and Design area - AUD - CAPES - Quadrennial Assessment (2017-2020). Collaborating Professor in the Academic Master's Degree in Development, Technologies, Society - Federal University of Itajubá - UNIFEI. Visiting Professor at the Center for Advanced and Sustainable Manufacturing Studies in the Postgraduate Doctorate Programs in Industrial Technologies and Processes and in the Master's Degree in Computer Aided Engineering at the University of Matanzas - CEFAS-UMCC - CUBA. He has experience in teaching, research and extension activities in the areas of Production Engineering, Industrial Design and Materials, with an emphasis on Management of Technological Innovation and Sustainability, Technology in Production Systems, Social Technologies, Design and Selection of Materials.

Danilo Corrêa Silva, Universidade da Região de Joinville - UNIVILLE

Coordinator of the Postgraduate Program in Design - Professional Master's. Adjunct professor in the Postgraduate Program in Design at Univille, in Joinville/SC. Member of the Univille Research Ethics Committee. PhD in Design from the Postgraduate Program in Design at FAAC/UNESP - Bauru campus. Works in the area of Design (Industrial Design), with an emphasis on research and application of new materials in product design.

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Published

2024-02-29

How to Cite

Ligabo Jr., N., de Jesus Silva, J. W., Ribeiro, R. B., & Silva, D. . C. (2024). DEVELOPMENT OF ADDITIVE BIOPOLYMER HEALING COVERAGE WITH ALOE VERA. Refas - Revista Fatec Zona Sul, 10(3), 1–23. https://doi.org/10.26853/Refas_ISSN-2359-182X_v10n03_06

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Vol. 10 No. 3 (2024)

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